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Instructions for use Zoloft

Sertralin

Sertralin

Bioavailability: 0-50%

ATC-Code: N06AB06

Protein binding: ≥ 90%

Metabolism: Liver

Metabolites: Norsertralin

Half-life: 23-26 hours

Excretion: Kidneys

CAS number: 79617-96-2

PubChem-CID: 68617

Drug Bank: DB01104

ChemSpider: 61881

UNII: QUC7NX6WMB

KEGG: D02360

ChEBI: CHEBI:9123

ChEMBL: ChEMBL809

Formula: C17H17Cl2N

Molar mass: 306,23 g·mol−1

How does it work?

The drug Zoloft has a mood-enhancing, activating and anxiolytic effect. The active ingredient sertraline inhibits the reuptake of serotonin. This leads to an increase in the amount of serotonin between brain cells.

How is it used?

The tablets should be taken with a glass of water at the same time each morning or evening. It does not matter if this medicine is taken before or after the meal.

The dose depends on your age, condition and whether or not you are taking other medicines.

For depression,the usual starting dose for adults is one 50 mg tablet a day. The dose can be gradually increased up to 200 mg per day if needed.

For the treatment of OCD in children between the ages of 6 and 12, the usual starting dose prescribed is 25 mg per day, which is half a 50 mg tablet. Adults and adolescents aged 13 to 18 should initially take one 50 mg tablet daily.

When adults suffer from panic disorder or social phobia, the usual starting dose of 25 mg per day is prescribed. After a week of treatment, the daily dose should be increased to 50 mg.

Side effects

Schlaflosigkeit
Insomnia

Schwindel
Dizziness

Kopfschmerzen
Headache

Übelkeit
Nausea

Durchfall
Diarrhea

Mundtrockenheit
Dry mouth

Erektionsstörungen
Ejaculation problems

Schwäche
Fatigue

Warnings and Precautions

seizures

Epileptic seizures may occur during treatment with Zoloft. For this reason, Zoloft tablets are contraindicated in unstable epilepsy. Caution should be exercised in patients with controlled epilepsy during Zoloft therapy. If epileptic seizures occur, treatment with Zoloft medication should be initiated.

Suicidal thoughts

Depressive disorders are usually associated with an increased risk of suicide, suicidal thoughts and suicide attempts. Therefore, patients should be monitored at the start of treatment and after dose adjustments.

Children and young people

Zoloft is not suitable for children and adolescents under the age of 18, with the exception of patients with OCD aged 6 to 17.

Other trade names

Adjuvin Sertralin-Generika Tresleen Asentra Gladem

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Contraindications

Hypersensitivity to the ingredients

Simultaneous administration with MAO inhibitors

Simultaneous use with pimozide

Pregnancy

Not safe

Alcohol

Alcohol consumption should be avoided

What happens if you miss the dose?

If you miss a dose, do not take twice as much the next time, but take it as described in the dosage instructions or as instructed by your doctor

Overdose

If you take more than you should, gastrointestinal upset may occur.

Interactions

There is a risk of serious interactions. Therefore, regular medical monitoring is required.

Unwanted reactions

Priapism

Severe skin reactions

Suicidal thoughts

Hallucinations

Aggression

Food

You should avoid grapefruit and grapefruit juice

Storage

Keep this medicine out of the sight and reach of children.

The medicinal product must be stored away from heat.

Frequently Asked Questions

What is Zoloft?

Zoloft is a medication used to treat and prevent major depression, obsessive-compulsive disorder, panic disorder, and anxiety disorders.

What is the name of the active ingredient in Zoloft?

The active substance is called sertraline. Sertraline belongs to the class of selective serotonin reuptake inhibitors.

In which dosage forms can you buy Zoloft?

It is available as film-coated tablets and concentrate for oral solution.

In what strengths can you buy Zoloft film-coated tablets?

Zoloft is commercially available as 50 mg and 100 mg film-coated tablets.

What does Zoloft price depend on?

The price primarily depends on the dosage and package size in which you buy the drug Zoloft. It also matters where you buy it. Internet pharmacies usually offer Zoloft cheaper than on-site pharmacies.

Can you buy Zoloft over the counter?

No, Zoloft medication is only available with a prescription from a doctor.

Why to buy Zoloft?

Zoloft is an antidepressant and belongs to a group of medicines called selective serotonin reuptake inhibitors. Its active ingredient blocks the reuptake of a chemical called serotonin in nerve cells in the brain.

Zoloft medication is used in the following cases:

  • for the treatment and prevention of depressive episodes of any severity;
  • to treat obsessive-compulsive disorder in adults and children aged 6 to 17;
  • in panic disorder (with or without agoraphobia);
  • in the case of post-traumatic stress disorder;
  • against social phobia.

The drug Zoloft should not be used in children and adolescents under the age of 18 to treat conditions other than obsessive-compulsive disorder because safety and efficacy in this age group have not been satisfactorily demonstrated. As for obsessive-compulsive disorder, Zoloft medication is not suitable for children under the age of 6 years.

This medicine can only be obtained with a prescription. There is no evidence that Zoloft is addictive.

Where to buy Zoloft cheaply?

Zoloft is considered a prescription drug in most countries. You will not find a local pharmacy that sells Zoloft tablets without first submitting a prescription.

Zoloft's price range is relatively wide depending on who makes it and who sells it. The price also depends on dosage and package size. In the stationary pharmacies this drug can be very expensive. If you want to buy Zoloft cheaply, choose an online supplier. There are numerous online vendors that sell Zoloft online. But not all of these ISPs can be considered as good quality sources. That's why you have to choose a reputable provider that you can trust.

The price of Zoloft 50 mg on the web ranges from €101.14 per 100 tablets, sometimes even more. A pack of 50 often costs between €48.78 and €78.02.

Some online pharmacies often offer discounts for large orders.

What is the difference between Zoloft and Sertraline?

Zoloft medicine is one of the trade names of sertraline. In addition to Zoloft, sertraline is marketed under the names Sertra, Sertralon, and generic sertraline. The differences between Zoloft and sertraline are in a few aspects like name, appearance and price; in others such as in the active ingredients and function, there are almost none.

Can you gain or lose weight on Zoloft?

Some antidepressants are able to increase body weight. Zoloft medication, as a rule, rarely increases body weight. Only 17 percent of the patients who shared their experiences with Zoloft on the health portal Sanego experienced weight gain. Like other SSRIs, Zoloft can often cause unwanted weight loss.

What side effects are possible after taking Zoloft tablets?

The most common side effects in adults treated with Zoloft are:

  • nausea
  • fatigue
  • loss of appetite
  • fear
  • diarrhea
  • excessive sweating
  • indigestion
  • change in sleeping habits, including increased sleepiness or insomnia
  • trembling or shaking
  • sexual disorders, including decreased libido and ejaculation failure

In children and adolescents treated with Zoloft, side effects were generally similar to those in adults, with the following additional side effects: nosebleeds, bladder weakness, aggressive reaction, and weight change.

Some side effects can be serious. If you experience any of the following symptoms, call your doctor right away:

  • abnormal bruising and bleeding
  • seizures
  • Hallucinations, confusion, loss of coordination, restlessness, fever, sweating, fast heartbeat, tremors, severe muscle stiffness or twitching, nausea, diarrhea or vomiting
  • headache, weakness, unsteadiness, or memory problems
  • difficulty breathing
  • swelling
  • skin rash

Zoloft tablets can also cause other side effects.

What medications does Zoloft interact with?

Some medicines can interact with the drug Zoloft and affect its effectiveness.

Before buying and taking Zoloft, tell your doctor or pharmacist if you are taking any of the following medicines:

  • other medicines used to treat depression belonging to MAO inhibitors. Taking Zoloft at the same time as an MAOI or within 14 days of stopping the MAOI can cause fever, extremely high blood pressure, and seizures.
  • other medicines for depression, panic disorder, social anxiety disorder, or obsessive-compulsive disorder (eg, Prozac, Luvox, Prothiaden, Aropax, Cipramil, Efexor XR, Xydep)
  • strong pain relievers such as fentanyl, tramadol, tapentadol or pethidine
  • Medicines for premenstrual dysphoria (eg, Prozac, Lovan, Xydep)
  • other medicines to relieve pain, swelling, and other symptoms of inflammation, including arthritis (eg, aspirin or NSAIDs such as ibuprofen or diclofenac)
  • weight loss drug phentermine
  • Medicines used to treat psychosis such as clozapine, which is used to treat schizophrenia
  • Drugs for irregular heartbeat (e.g. Tambocor)
  • antibiotics
  • ADHD medications such as dexamphetamine and lisdexamphetamine
  • tryptophan
  • Lithium, a medicine used to treat mood swings
  • dextromethorphan
  • methadone (used to treat drug addiction)
  • St. John's wort (used to treat mood disorders)
  • Warfarin (e.g. Marevan, Coumadin) or other medicines that prevent blood from clotting
  • Diazepam or other CNS-acting drugs (eg, Serepax, Valium)
  • pimozide (used to treat emotional, behavioral and thinking disorders)
  • Sumatriptan (e.g. Imigran), a medicine used to treat migraines
  • phenytoin (e.g. Dilantin), a medicine used to treat epilepsy
  • Cimetidine (e.g. Tagamet).

Some drug combinations can increase the risk of serious side effects and are potentially life-threatening. Provide information about all prescription and over-the-counter medications you are taking or using.

Resources

  1. Sertraline: Side Effects, Uses, and Dosage - Drugs.com
  2. Review: RM Hirschfeld: Sertraline in the treatment of anxiety disorders. In: Depression Anxiety. 11 (4), 2000, pp. 139-157
  3. Mutschler, E.: Drug Effects, Scientific Publishing Company Stuttgart, 10th edition, 2013
  4. NPS Medicinewise : About Zoloft tablets
Reviews

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5

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I've been on Zoloft for almost two months and I give this drug a 5 out of 5 because I feel great about it! At the same time as taking this medication, I created my own treatment plan: I drink 2 liters of water a day, sleep for 8 hours, have cognitive behavioral therapy, have avoided alcohol, caffeine and sugar. I eat a lot of vegetables, fish, fruit and nuts, exercise 3 times a week, take vitamin D, B12 and magnesium. All this helps me well against depression.

11.05.2022

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