Patent: Patent expired
Producer: Pfizer Pharma GmbH
Dosage: 0.25mg, 0.5mg, 1mg, 2mg
Dosage form: tablet
Unit of measurement: mg
Active ingredient: alprazolam
Anxiety disorders, Generalised anxiety disorder, Panic disorders
Drug class: benzodiazepines
Onset of action: 60-120 minutes
Duration of action:
Protein binding: ≥ 80%
Metabolites: alpha-hydroxyalprazolam, 4-hydroxyalprazolam, beta-hydroxyalprazolam
Half-life: 11-13 hours
CAS number: 28981-97-7
Drug Bank: DB00404
Molar mass: 308,76 g·mol−1
Xanax is a central nervous system depressant. The central nervous system is responsible for maintaining our body's main functions, including the regulation of heart rate, breathing, blood pressure, and body temperature. When Xanax is ingested, it slows down these functions.
When you experience excessive stress or anxiety, the brain increases certain nerve signals that lead to feelings of anxiety. During this time, the brain produces an unbalanced amount of chemical signals, which increases brain activity, feelings of anxiety and fear, and limits the ability to calm the mind.
Xanax pills have a calming effect by interfering with the effects of gamma-aminobutyric acid (GABA), a naturally occurring chemical in the brain. Said to be our natural tranquilizer, GABA is found in 80% of the brain's nerve connections. When you get anxious or nervous, your brain releases it to calm the negative activity. If you suffer from anxiety or panic disorder, Xanax binds to these receptors and stimulates their signals.
The starting dose for adults is 0.25 to 0.5 mg three times a day. If necessary, the dose can be increased at 3-4 day intervals to a maximum dose of 4 mg daily.
The maintenance dose is 0.5 mg to a maximum of 3 mg per day, divided into several individual doses.
Xanax can be taken with or without food.
Hypersensitivity to the ingredients
Concomitant use with certain drugs
Xanax is contraindicated if you are taking antifungal medications including ketoconazole or itraconazole.
Avoid during pregnancy
Alcohol consumption increases the side effects of medication
You can make up for the missed application during the day and continue to use the dose prescribed by your doctor as usual on the following day.
If you take more of this medicine than you should, it could cause serious side effects.
There is a risk of significant interactions. Therefore, medical supervision is recommended.
Food does not affect the effects of the drug.
Keep this medicine out of the sight and reach of children.
Store in the original package in order to protect from light and moisture.
Store the medicine at normal room temperature.
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Xanax is an anti-anxiety drug from the benzodiazepine group. This is the same group that includes diazepam (Valium), clonazepam (Klonopin), lorazepam (Ativan), flurazepam (Dalmane), and other drugs. The active ingredient in Xanax is called Alprazolam.
The drug is FDA-approved for the treatment of anxiety disorders, specifically generalized anxiety disorder and panic disorder.
In addition to these uses, Xanax pills are commonly used off-label for other clinical purposes:
Xanax is marketed as tablets in 4 strengths (0.25 mg, 0.5 mg, 1 mg and 2 mg). The tablets are available in different shapes and colors depending on the strength. The 2 mg tablets are white, green or yellow in color and rectangular in shape. In other dosages, the tablets are oval and colored white (0.25 mg), orange (0.5 mg) or blue (1 mg).
After taking Xanax, the effects are usually felt within one to two hours. Xanax stays in a patient's body for 12 to 15 hours.
Taking the Xanax pills regularly for a long time will undoubtedly produce the side effects. Side effects on the body include euphoria, excessive drowsiness, problems concentrating, nausea, headaches and memory problems. Psychologically, patients may have relationship problems, work problems, financial difficulties, and a loss of motivation in daily life.
Xanax use leads to forgetfulness, ie patients simply cannot remember conversations or routine tasks. Impaired motor skills are also common. The sedation can occasionally last for several days. The serious side effects are slow breathing, coma, and - in some cases - even death.
Alcohol enhances the effects of Xanax pills and slows down its elimination from the body. If you take the medicine and then drink alcohol, you may experience extreme lethargy and permanent memory loss.
It is recommended not to combine the two substances. It is possible that the combination will lead to serious side effects. These side effects are:
Xanax can interact with many medications, including:
These drugs can slow down the elimination of Xanax from the body, which can eventually lead to overdose.
Such drugs as ketoconazole (trade name Nizoral Tablets), itraconazole (Sporanox), cimetidine (Tagamet), nefazodone (Serzone) and fluvoxamine (Luvox) increase its plasma concentration when co-administered with Xanax and may therefore increase the side effects of Xanax tablets.
Xanax interacts with alcohol and drugs (e.g., barbiturates and narcotics) that have an inhibitory effect on the CNS, increasing their effects and causing sedation.
Carbamazepine and rifampin reduce the effects of alprazolam by increasing metabolism and eliminating alprazolam in the liver.
Talk to your doctor or pharmacist about any medications you are currently taking to make sure they do not interact.
Suddenly stopping the drug Xanax after prolonged use can lead to withdrawal symptoms such as:
The seizures are possible in more severe cases of withdrawal. In order to avoid the withdrawal syndrome, patients should reduce the dose gradually under medical supervision instead of stopping the drug abruptly.
Regular use of the drug Xanax can lead to addiction. People with drug addiction or a history of drug abuse are particularly at risk of becoming addicted to Xanax and other benzodiazepines. In addition, every patent can be exposed to a risk of abuse.
According to a study, using alprazolam for more than four weeks can cause the body to produce fewer of its own GABA chemicals, leading to tolerance and dependence on the drug. This means that the person taking it feels like they need more of the drug to get the same effect. As the tolerance and addiction to the drug increases, the person tries more and more to feel the same way, thereby becoming dependent on the substance.
Been taking Xanax for 3 months. The daily dose is 2mg. I have practically no side effects with it.
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