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Instructions for use Vermox

Mebendazol

Mebendazol

Other names: Methyl-5-benzoyl-2-benzimidazolcarbamat

Bioavailability: 0-50%

ATC-Code: P02CA01, QP52AC09

Protein binding: ≥ 90%

Metabolism: Liver

Metabolites:

Half-life: 3-6 hours

Excretion: Feces

CAS number: 31431-39-7

PubChem-CID: 4030

Drug Bank: DB00643

ChemSpider: 3890

UNII: 81G6I5V05I

KEGG: D00368

ChEBI: CHEBI:6704

ChEMBL: ChEMBL685

ECHA-InfoCard: 100.046.017

Formula: C16H13N3O3

Molar mass: 295,29 g·mol−1

How does it work?

The Vermox anthelmintic contains the substance mebendazole, which prevents the worms from absorbing the sugars that are essential for their survival. This depletes the worms' energy stores and leads to their death within a few days. The dead worms are then passed out of the intestine with the stool. Although the active ingredient mebendazole kills the adult worms, it does not kill their eggs. It is therefore very important to follow the hygiene measures very thoroughly even after the treatment. This will help prevent you from swallowing eggs, which can then lead to the new worm infection.

How is it used?

Vermox can be taken with a meal or on an empty stomach. The tablets can be crushed or chewed if necessary to make them easier to swallow. The dose of Vermox depends on the type of worm infection.

For the treatment of pinworms, adults and children over 2 years old should take one 100 mg tablet on the first day, then one tablet 2 weeks later and a third tablet 4 weeks after the first tablet. The first dose kills the worms but not the parasite eggs. The second dose will get rid of any worms that may have hatched from the eggs. The 3rd dose ensures that all worms are gone.

To treat other types of worm infestations, patients should take Vermox 100 mg (1 tablet) twice a day for 3 days. If symptoms persist after 3 weeks, a second course of treatment may be postponed.

The dosage is related not only to the type of infection, but also to the patient's body weight, presence of concomitant diseases and use of other medications.

Side effects

Bauchschmerzen
Stomach pain,
Upper abdominal complaints,
abdominal discomfort

Durchfall
Diarrhea

Magenschmerzen
Flatulence

Übelkeit
Nausea,
Vomit

Warnings and Precautions

Caution in severe liver dysfunction

In the case of liver dysfunction, Vermox tablets should only be taken with particular caution and after a strict benefit-risk assessment by the doctor.

Possible interactions with other drugs

Simultaneous administration of Vermox 100mg and metronidazole should be avoided. Caution is advised when Vermox tablets are taken concomitantly with immunosuppressants, especially glucocorticoids. Because of the interactions, this combination is recommended.

Other trade names

Surfont Pantelmin

Contraindications

Hypersensitivity to the ingredients

Pregnancy

Not safe

Alcohol

No interactions with alcohol

What happens if you miss the dose?

You can make up for the missed application during the day and continue to use the dose prescribed by your doctor as usual on the following day.

Overdose

If you take more than you should, tell your doctor. There could be side effects.

Interactions

There is a risk of significant interactions. Therefore, medical supervision is recommended.

Unwanted reactions

Seizure

Dizziness

Hepatitis

Skin rash

Severe skin reactions

Food

Food does not affect the effects of the drug.

Storage

Store in the original package in order to protect from light and moisture.

Frequently Asked Questions

Vermox when are worms dead?

Vermox 100mg vermifuge does not kill worm eggs. For this reason, another dose should be taken 2 weeks later to prevent re-infection.

How fast does Vermox work?

Vermox tablets should work immediately. Please note, however, that it may take several days before you become worm-free.

How does Vermox work?

The active ingredient in Vermox attacks the intestines of the worms and prevents them from eating. This will kill the worms. After a few weeks, the worms are passed out of the body with the stool.

How much does Vermox cost?

Vermox price varies from supplier to supplier and depends on Vermox dosage and package size.

Can you buy Vermox tablets without a prescription?

You can buy Vermox at the pharmacy for adults and children over 2 years old. It is only available by prescription. There are also other commercial preparations with the same active ingredient: Vermox forte 500 mg, Pantelmin, Surfont.

Can you buy Vermox online?

Can you buy Vermox online? You can buy Vermox online if you already have a valid prescription from your doctor. In any case, if you have a conventional prescription, you must send in your prescription. You can easily buy Vermox with an e-prescription. Your e-prescription can be redeemed quickly and securely. Scan it with your camera or upload it as a file when ordering. Or you can get your e-prescription from a telemedicine company and have Vermox tablets mailed to you.

What is Vermox?

Vermox® is a drug used to treat worm infections in adults and children over 2 years of age. This broad-spectrum anti-wormer is prescribed to treat the following types of intestinal worm infections:

  • roundworm infections;
  • hookworm infections;
  • whipworm infections.
  • pinworm infections
  • tapeworm infections
  • Dwarf nematode infections.

Vermox is available commercially in the form of 100 mg tablets and 100 mg suspensions in 5 mL. It contains mebendazole as an active ingredient.

Are Vermox tablets available over the counter?

Throughout Germany, as well as in many other EU countries, Vermox requires a prescription. This means that you cannot buy Vermox without a prescription. However, many internet pharmacies offer Vermox over the counter. Caution is advised as there are many counterfeit medicines on the web. By buying Vermox , you are choosing a reputable online pharmacy.

Vermox or Helmex: which is better?

The effectiveness of Vermox (active substance mebendazole) and Helmex (active substance pyrantel) was examined in two groups of 59 and 58 cases of patients with intestinal parasitosis. Mebendazole had a success rate of 96%, 82.2%, 71.4%, and 66.6% in the treatment of roundworm, hookworm, Trichuris trichiura (trichuriosis) infection, and dwarf nematode, respectively. The corresponding success rates of pyrantel were 92.6%, 85.7%, 19.4% and 0%. Pyrantel (Helmex) is believed to have no significant effect on Trichuris trichiura and dwarf nematodes. Neither drug had any effect on beef tapeworms.

Helmex (Pyrantel) is recommended to be used as a drug of choice in several parasitic infections except for Trichuris trichiura and dwarf roundworms. For those patients who have Trichuris trichiura and dwarf roundworms, Vermox (Mebendazole) is more suitable. Vermox can be prescribed for the patients with clinical evidence of worm infections even if stool examination is not possible because it covers almost the entire range of common worm infections.

Is it safe to take Vermox during pregnancy?

The safety of use during pregnancy has not been established. The manufacturer states that this anthelmintic should not be taken by women who are pregnant or think they may be pregnant.

Studies involving around 1,650 women who took Mebendazol Vermox 100mg during the first trimester found that these women did not appear to be more likely to have a baby with a birth defect.

Studies in a small number of pregnant women taking mebendazole in the first few weeks of pregnancy have not shown an association with miscarriage.

A study of around 2,500 pregnant women taking Vermox found no association with stillbirth, premature birth (less than 37 weeks gestation) and very low birth weight (less than 1,500g) for the baby.

Since little information is available about the safety of Vermox tablets in pregnancy, the hygiene measures for the treatment of worm infestation in early pregnancy should be observed if possible and Vermox should only be used after the first 12 weeks of pregnancy.

If your doctor prescribes mebendazole-containing preparation Vermox during pregnancy, it is because the benefits outweigh the risks.

Is Vermox anthelmintic suitable for children?

Vermox tablets are suitable for children from 2 years and adults. The safety and effectiveness of using this medicine in children under 2 years of age have not been established. Vermox may be considered for children 1 to 2 years of age if the benefits outweigh the potential risks to the child. Seizures have been reported very rarely when children, including children under 1 year of age, have been treated. Therefore, Vermox 100mg is contraindicated for children under 1 year old.

itemizations

  1. N Islam, NA Chowdhury. Mebendazole and pyrantel pamoate as broad-spectrum anthelmintics
  2. Package leaflet for Vermox tablets
  3. NPS Medicinewise : Vermox tablets
  4. Van den Bossche H, Rochette F, Hörig C. Mebendazole and related anthelmintics. Adv Pharmacol Chemother, 1982, 19, 67-128
Mary Jackson
Master student
She studies medicine at the Institute for Translational Immunology (TIM). Since 2021 freelance author at Compharms.
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After receiving several anti-worm medicines and nothing really helped, I tried Vermox. Yes, I was struggling with nausea and stomach ache and even had to throw up in the evening, but after that my subtenants finally left.

05.11.2021

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