Tapentadol vs Tramadol

Which painkiller is better and more effective: tapentadol vs tramadol? Are there differences in areas of application, side effects, etc.

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Tapentadol vs Tramadol
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Rating
5
4.8
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Total number of ratings
5
Stephanie

I was critical because I read again and again that tramadol can be addictive. After consulting my doctor, I still decided to take tramadol because the back pain was very severe. After short-term treatment with this drug, the pain was successfully relieved.

15.12.2021
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4.8
Amelie

Palexia was prescribed by my doc for severe osteoarthritis. Here it is important to find the right dose. I take 150 mg tapendapol and I`m fine with it. Thank goodness the headache didn`t last long.

03.03.2021
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Availability
in 0 Pharmacy(s)
in 0 Pharmacy(s)
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Price (per pack)
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Price (per 1 dose)
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Brand
Generic
Generic
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ATC-Code
N02AX02
N02AX06
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Onset of action
30-60 minutes
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Duration of action
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4-6 hours
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Interactions
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What happens if you miss the dose?
If you miss a dose, do not take twice as much the next time, but take it as described in the dosage instructions or as instructed by your doctor
Do not apply a double dose if you have forgotten the previous application, but continue as before.
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Pregnancy
Avoid during pregnancy
Not safe
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Alcohol
Alcohol consumption increases the side effects of medication
Alcohol consumption increases the side effects of medication
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Unwanted reactions
Nausea
Vomit
Constipation
Headache
Anxiety
Headache
Dry mouth
Fatigue
Sleepiness
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Application areas
Acute pain
Severe pain
Acute pain
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Contraindications
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Active ingredient
tramadol
tapentadol
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OtherDrugName
Tramal
Contramal
Adamon
Ecodolor
Amadol
Jutadol
Lanalget
Noax
Nobligan
Tramal-long
Tradolan
Tradonal
Tramagit
Tramundin
Travex
Palexia
Yantil
Nucynta
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Overdose
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Producer
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Warnings and Precautions
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Side effects
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Storage
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Dosage
50
100
150
200
50
100
150
200
250
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Dosage form
film-coated tablet(s)
Extended release tablet
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Unit of measurement
mg
mg
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Drug class
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Other names
[2-(Dimethylaminomethyl)-1-(3-methoxyphenyl)cyclohexanol]
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Prescription only
Prescription only
Prescription only
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Patent
Patent expired
Patent expired
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Bioavailability
varies
0-50%
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Metabolism
Liver
No data available
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Metabolites
O-desmethyltramadol, N-desmethyltramadol
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Half-life
6.3 ± 1.4 hours
4 hours
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Excretion
Urine
Urine
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Protein binding
≥ 20%
≥ 20%
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CAS number
27203-92-5
175591-09-0
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Pub Chem
33741
9838022
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Drug Bank
DB00193
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Chem Spider
31105
8013742
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UNII
39J1LGJ30J
H8A007M585
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Chembi
CHEBI:9648
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Chembl
ChEMBL1066
ChEMBL1201776
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ECHA-InfoCard
100.043.912
100.131.247
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Formula
C16H25NO2
C14H23NO
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Molar mass
263,38 g/mol
221.344 g·mol−1
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