Sildenafil Basics Price

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Instructions for use Sildenafil Basics

Sildenafil

Sildenafil

Bioavailability: 0-50%

ATC-Code: G04BE03

Protein binding: ≥ 90%

Metabolism: Liver

Metabolites: N-desmethylsildenafil

Half-life: 3-4 hours

Excretion: Feces

CAS number: 139755-83-2

PubChem-CID: 135398744

KEGG:

Formula: C22H30N6O4S

Molar mass: 474,58 g·mol−1

How does it work?

Sildenafil Basics is a potent, selective cyclic guanosine monophosphate (cGMP) specific inhibitor of phosphodiesterase type 5 (PDE5).

The physiological mechanism of erection is based on the release of nitric oxide (NO) in the erectile tissue during sexual stimulation. This, in turn, leads to an increase in cGMP levels, resulting in relaxation of smooth muscle tissue in the cavernous bodies and an increase in blood flow in the cavernous bodies of the penis.

Sildenafil Basics 100mg/ 50 mg does not have a direct relaxing effect on the corpus cavernosum but enhances the relaxing effect of nitric oxide by inhibiting PDE 5, which is responsible for breaking down cGMP in the corpus cavernosum.

In vitro studies have shown that sildenafil acts selectively against PDE5. Its activity compared to other known phosphodiesterases is much lower.

A prerequisite for the effectiveness of Sildenafil Basics 50 mg/ 100mg is sexual stimulation.

The use of Sildenafil Basics in doses up to 100 mg resulted in a slight, transient decrease in blood pressure. The antihypertensive effect is due to the vasodilating effect of Sildenafil Basics, which is accompanied by an increase in the level of cGMP in vascular smooth muscle cells.

A mild and transient impairment of color perception (blue/green) was noted in some patients 1 hour after administration of Sildenafil Basics 100mg. Color perception was restored after two hours. Color vision impairment is caused by inhibition of PDE 6, which is involved in the transmission of light in the retina. Sildenafil has no effect on visual acuity, contrast perception, electroretinogram values, intraocular pressure or pupil diameter.

You can buy Sildenafil Basics in 2 strengths. That's 50 mg and 100 mg. The patient thus has 2 dosage options for erectile dysfunction. It is available in different pack sizes. When you buy Sildenafil Basics 100mg 90 tablets you can save a lot if you compare the basic price for one tablet in a pack of 4.

Do you want to buy Sildenafil Basics 100mg/ 50 mg or Viagra online? Both medications are available in pharmacies on presentation of a prescription.

How is it used?

The ED drug is taken orally. For most adult patients, the recommended dose of Sildenafil Basics 50 mg is approximately 30-60 minutes before sexual activity. The dose can be increased to 100 mg or reduced to 25 mg depending on effectiveness and tolerability. The maximum recommended dose is Sildenafil Basics 100mg. This medicine should not be used more than once a day.

No dose adjustment is required in mild to moderate renal impairment (CrCl 30-80 ml/min). In severe renal insufficiency (CrCl <30 ml/min), the dose of Sildenafil Basics should be reduced to 25 mg.

In patients with liver damage (especially with cirrhosis), the excretion of Sildenafil Basics is impaired, so the dose should be reduced to 25 mg.

There is no need to adjust the dose of Sildenafil Basics in elderly patients.

Using Sildenafil Basics with other medicines

When used concomitantly with ritonavir, the maximum single dose of Sildenafil Basics should not exceed 25 mg. The frequency of application in this case should be once every 48 hours.

When used with CYP3A4 inhibitors (eg, erythromycin, ketoconazole (Nizoral tablets), saquinavir, itraconazole), the starting dose of Sildenafil Basics is 25 mg.

To minimize the risk of postural hypotension in patients taking alpha-blockers, Sildenafil Basics should be initiated only after haemodynamic stabilization has been achieved in these patients. Reducing the starting dose of sildenafil should also be considered.

Side effects

Kopfschmerzen
Headache

Übelkeit
Nausea

Hitzewallungen
Hot flashes

Gesichtsrötung
Facial flushing

Magenschmerzen
Indigestion

Sehstörungen
Visual disturbances,
Blurred vision

verstopfte Nase
Stuffy nose

Schwindel
Dizziness

Warnings and Precautions

Simultaneous use of alpha blockers

Concomitant use of other PDE5 inhibitors or other treatments for erectile dysfunction

Possible interactions with other drugs

Risk of low blood pressure

Beware of the liver problems

Be careful if you have heart disease

Other trade names

Viagra® Fildena Kamagra Viagra Connect

Contraindications

Acute renal failure

Impaired liver function

Impaired kidney function

Intake of nitrates

Increased intraocular pressure

Heart attack

Liver cirrhosis

Blood cell problems such as sickle cell disease, multiple myeloma or leukemia

Contraindicated in women

Stroke

Pregnancy

Not safe

Alcohol

Alcohol consumption increases the side effects of medication

What happens if you miss the dose?

Do not take a double dose to make up for a forgotten dose. For the next dose, do not take more than the usual recommended amount.

Overdose

Abdominal pain, nausea, vomiting and diarrhea are possible. Blood vomit and blood in the stool can be life-threatening.

Overdose can cause headaches, nasal congestion, and blurred vision.

Overdosing can cause side effects.

Interactions

There is a risk of significant interactions. Therefore, medical supervision is recommended.

Unwanted reactions

Stomach pain

Chest discomfort

Vomit

Diarrhea

Palpitations

Muscle aches

Food

The effect of the drug is influenced by the food.

Storage

Keep this medicine out of the sight and reach of children.

The medicinal product must be stored away from heat.

Store in the original package in order to protect from light and moisture.

Frequently Asked Questions

What is the name of the manufacturer of Sildenafil Basics?

The manufacturer is Basics GmbH based in Leverkusen. This German manufacturer is owned by Sun Pharmaceutical Industries Ltd, founded in 1983. based in India. It is one of the largest manufacturers of generic drugs in the world. In 2008 his subsidiary Sun Pharmaceuticals Germany GmbH was founded with headquarters in Kirchzarten.

What is Sildenafil Basics?

Sildenafil Basics is a generic Viagra. It has the same active ingredients and is therapeutically equivalent to Pfizer's branded drug Viagra. But you can buy Sildenafil Basics much cheaper. This is important because statutory health insurance companies do not cover the costs of sexual enhancers. Many men are happy that they can get a sexual enhancer very cheaply.

Is Sildenafil Basics divisible?

Sildenafil Basics are red, rounded, triangular, film-coated tablets imprinted with “S23” (Sildenafil Basics 100 mg) or “S22” (Sildenafil Basics 50 mg) on one side and plain on the other side. There is no break line. Therefore, Sildenafil Basics 100 mg or 50 mg cannot be divided.

Can you buy Sildenafil Basics 100mg without a prescription?

No. You can only buy Sildenafil Basics with a private or health insurance prescription. This drug is subject to pharmacy and prescription requirements. Thus, Sildenafil Basics 100 mg is not available without a prescription.

Can you buy Sildenafil Basics 50 mg without a prescription?

No. A prescription is also required for Sildenafil Basics with a potency of 50 mg. It is available in pharmacies upon presentation of a valid prescription.

In what pack sizes can you buy Sildenafil Basics 100 mg?

You can buy Sildenafil Basics 100 mg in the following pack sizes: 4 tablets, 12 tablets, 20 tablets, 24 tablets, 48 tablets, 60 tablets, 90 tablets. Not all pack sizes may be marketed.

What is the price of Sildenafil Basics 100 mg?

A pack of 4 costs €15.03. The basic price is €3.76 / 1 tablet. The price for a pack of Sildenafil Basics 100mg 12 tablets is €17.99. In this pack size, the basic price is cheaper and is €1.50 / 1 tablet. The larger the pack, the cheaper the basic price for a tablet.

What is the price of Sildenafil Basics 50 mg?

A pack of 4 costs €13.53. The basic price is €3.38 / 1 tablet. The price for a pack of Sildenafil Basics 50 mg 12 tablets is €16.99. In the pack of 12, the basic price is cheaper and is €1.42 / 1 tablet. Sildenafil Basics 50 mg 90 tablet cost €65.65. The basic price is €0.73 / 1 tablet. You can really save a lot by buying a larger pack.

Why to buy Sildenafil Basics?

Sildenafil Basics 100mg/ 50 mg is primarily used to treat erectile dysfunction, which is characterized by an inability to get and maintain an erection sufficient for satisfactory sexual intercourse. Sildenafil Basics helps achieve an erection when the user is sexually stimulated or has sexual desire.

Sildenafil Basics works just as well as Viagra and other sildenafil-containing generics (e.g. Fildena). Compared to Viagra, this drug is cheap. While the little blue pill is still manufactured by Pfizer, other companies around the world and in Germany also produce sildenafil. It may look different, but it's still an effective treatment option for erectile dysfunction.

Alternative products with the same active ingredient

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Sildenafil Basics Price

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I take a dose of Sildenafil Basics 50mg once before intercourse. This dose is quite enough for multiple rounds over a period of 8-9 hours. And it`s all very affordable for me.

08.05.2022

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