Other names: 1,4-Pregnadien-11β,17α,21-triol-3,20-dion
ATC-Code: A07EA01, C05AA04, D07AA03
Protein binding: ≥ 60%
Half-life: 2-3.5 hours
CAS number: 50-24-8
Drug Bank: DB00860
Molar mass: 360.450 g·mol
Prednisolone is a synthetic hormone (steroid) and an analogue of the hormone cortisol secreted by the adrenal cortex. Prednisolone used to treat various diseases.
Prednisolone acts as an immunosuppressant. The immune system protects the body from bacteria and viruses. In certain diseases, however, the immune system produces the antibodies and perceives the body's own cells as foreign bodies. This mechanism underlies autoimmune diseases.
The drug has a pronounced anti-inflammatory effect and inhibits the development of symptoms of inflammation (redness, swelling, pain). Symptoms such as muscle weakness and short-term fatigue can occur when you start taking prednisolone.
Prednisolone tablets should be swallowed whole with a full glass of water during or immediately after a meal. Always take prednisolone exactly as your doctor has told you. The dose is set by the doctor individually and depends on the disease.
Prescribing should take into account the circadian rhythm of (GC) secretion: most of the dose (2/3) or the whole dose should be taken in the morning hours around 8:00 am and 1/3 in the evening. Weaning should be gradual.
Adults : In acute conditions and as replacement therapy, the starting dose is 20-30 mg per day. The daily maintenance dose is 5-10 mg. If needed, the initial daily dose can be around 15-100 mg and the maintenance dose can be around 5-15 mg/day.
Children : The initial daily dose is 1-2 mg/kg body weight divided into 4-6 divided doses. Daily maintenance dose is 300-600 µg/kg.
If you buy prednisolone and take it for hormone replacement therapy, then the recommended daily dose is 5-7.5 mg divided into 2 doses.
You can find more information on dosing for other diseases in the prednisolone package insert.
Particular caution in severe mental illness
Effects on eyesight
Hypersensitivity to the ingredients
Ask your doctor or pharmacist for advice before taking prednisolone.
Alcohol consumption should be avoided
Alcohol and prednisone can irritate the digestive tract and cause stomach ulcers. Combining the two can cause problems, especially if you're already prone to indigestion or an upset stomach. Prednisone can cause bones to become thin and brittle, potentially contributing to the early onset of osteoporosis.
You can make up for the missed application during the day and continue to use the dose prescribed by your doctor as usual on the following day.
Overdosing can cause side effects.
There is a risk of significant interactions. Therefore, medical supervision is recommended.
The effect of the drug is influenced by the food.
Keep this medicine out of the sight and reach of children.
This medicinal product does not require special storage conditions.
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Prednisolone is a synthetic drug from the group of glucocorticoid hormones. It was first synthesized in Germany in 1957 in the Merck laboratory. It is produced in the form of tablets, injection, skin cream and eye drops.
Prednisolone has anti-inflammatory, anti-shock, anti-allergic and immunosuppressive effects. Prednisolone is prescribed for diseases that require systemic treatment with glucocorticoids. These include the following diseases:
If you want to buy prednisolone tablets cheaply, then our price comparison is available to you. Thanks to our portal you can consider all the pharmacies that offer Prednisolone. Prednisolone tablets price varies greatly from online pharmacy to online pharmacy and is related to the dosage, package size and the manufacturer.
Prednisolone is an effective drug that helps me well. However, after a few days of taking it, I got side effects in the form of insomnia and nervousness. Recently I've been weaning again, down to 20 mg and then I have to wait and see. Depending on the results, I then have to stop prednisolone or take a basic dose.
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