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Instructions for use Penicillin


Bioavailability: 50-100%

ATC-Code: J01CE02

Protein binding: ≥ 80%

Metabolism: Liver


Half-life: 30-60 minutes

Excretion: Kidneys

CAS number: 87-08-1

PubChem-CID: 6869

Drug Bank: DB00417

ChemSpider: 6607

UNII: Z61I075U2W

KEGG: D05411

ChEBI: CHEBI:27446


ECHA-InfoCard: 100.001.566

Formula: C16H18N2O5S

Molar mass: 350.39 g·mol

How does it work?

The active ingredient is called phenoxymethylpenicillin. Phenoxymethylpenicillin is an oral antibacterial drug belonging to the penicillin group. It has a bactericidal effect, inhibits the synthesis of peptidoglycan of the bacterial cell wall, which leads to its destruction and the death of the bacterial cell.

The maximum plasma level is reached within 30-45 minutes after taking the drug.

Phenoxymethylpenicillin is eliminated primarily unchanged (25% of the ingested dose) and in the form of metabolites (35% of the ingested dose) via the kidneys; about 30% is excreted via the gastrointestinal tract.

How is it used?

The dosage depends on the type and sensitivity of the pathogen, the severity of the bacterial infection and the patient's medical condition.

Penicillin tablets are swallowed whole with a glass of water about an hour before meals. Children can take it during meals.

The daily dose is distributed evenly throughout the day in 3 to 4 individual doses, if possible at intervals of 8 hours. In the case of throat, nose and ear infections, the total daily dose is divided into 2 individual doses, if possible 12 hours apart.

The recommended dose for adults and children over 12 years of age is 295-885 mg of phenoxymethylpenicillin (0.5-1.5 million units) 3 to 4 times a day.

The recommended dose for children under 12 years of age depends on body weight and age.

The treatment usually lasts 7 to 10 days.

Side effects

Allergic reaction


loss of appetite

Stomach pain


Soft stool,

Warnings and Precautions

tendency to allergies

If you are prone to allergies, you should only buy and take penicillin with your doctor's consent.

Severe gastric and intestinal disorders

You should not take penicillin without medical advice if you have severe stomach and intestinal disorders with vomiting and diarrhea. Adequate absorption into the body is not guaranteed under these conditions, which may require discontinuation of treatment with penicillin.

Use of non-enzymatic methods for urine sugar determination

If non-enzymatic methods are used to measure urinary glucose, caution should be exercised during treatment with penicillin.

Caution with long-term use

Long-term treatment with penicillin can lead to superinfection with resistant bacteria.

Beware of heart disease

If you suffer from heart disease or severe electrolyte imbalances, caution is advised. Attention should be paid to the potassium intake from penicillin.

Other trade names

Ospen Oratren


Hypersensitivity to the ingredients




Alcohol consumption should be avoided

The effects of both substances can influence each other unfavorably.

What happens if you miss the dose?

Ask your doctor about this


If you take more than you should, tell your doctor. There could be side effects.


There is a risk of significant interactions. Therefore, medical supervision is recommended.

Unwanted reactions


Facial edema

Drug fever

Joint pain

Tongue swelling


The effect of the drug is influenced by the food.


Keep this medicine out of the sight and reach of children.

Do not store above +30°C

Frequently Asked Questions

Can you buy penicillin without a prescription?

No, the antibiotic penicillin is subject to a prescription in Britain.

In what dosage forms and dosages can penicillin be bought?

Penicillin is available in 1 Mega, 1.2 Mega and 1.5 Mega film-coated tablets and juice.

Was kostet Penicillin?

Penicillin price depends on dosage and package size.

Who Invented Penicillin?

Alexander Fleming accidentally discovered penicillin in 1928. In 1945 Fleming was awarded the Nobel Prize in Medicine.

Why buy penicillin?

Penicillin tablets are used to treat mild to moderate infections caused by pathogens susceptible to phenoxymethylpenicillin that respond to treatment with penicillin tablets, such as:

  • ENT infections;
  • respiratory infections;
  • skin infections;
  • maxillary sinus infection;
  • dental infections;
  • mouth infections;
  • bacterially caused inflammatory lymph node swelling;
  • Infections caused by group A β-hemolytic streptococci.

The antibiotic penicillin in the form of tablets is also used to prevent bacterial inflammation of the inner lining of the heart and to prevent a recurrence of rheumatic fever.

In addition to film-coated tablets, you can also buy penicillin in the form of juice/suspension/dry juice.

When not to buy penicillin tablets?

Like any antibiotic, penicillin has contraindications for use. Many people have an increased sensitivity to the drugs of the penicillin group and sulfonamides. Therefore, another antibiotic is recommended for such people. Penicillin tablets are not recommended for hay fever, bronchial asthma, hives and for pregnant women and nursing mothers.

Alcohol consumption is strictly prohibited during treatment with penicillin.

What alternative to buy penicillin?

As alternatives to penicillin, you can buy the antibiotics Zithromax, Augmentin, Amoxil, Doxycycline, Flagyl, Erythromycin or Ampicillin.


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1 Review(s)

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Hello, I have been taking penicillin tablets for severe tonsillitis for 3 days. My throat doesn`t hurt as much and my fever has gone down. As for side effects, I have the diarrhea but I want to continue the treatment.


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