Buy Nizoral Tablets Online

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Instructions for use Nizoral

Ketoconazol

Ketoconazol

Bioavailability: No

ATC-Code: J02AB02, D01AC08, G01AF11

Protein binding: ≥ 80%

Metabolism: Liver

Metabolites: N-Deacetyl Ketoconazol

Half-life:

Excretion: Biliary

CAS number: 65277-42-1

PubChem-CID: 3823

Drug Bank: DB01026

ChemSpider: 401695

UNII: R9400W927I

KEGG: D00351

ChEBI: CHEBI:48336

ChEMBL: ChEMBL75

ECHA-InfoCard: 100.059.680

Formula: C26H28Cl2N4O4

Molar mass: 531,43 g·mol−1

How does it work?

The active substance, ketoconazole, is believed to exert its antifungal effects by altering cell membranes, resulting in increased membrane permeability, secondary metabolic effects, and growth inhibition.

Although the exact mode of action of ketoconazole has not been fully determined, it has been suggested that the drug's fungistatic activity may result from a disruption in ergosterol synthesis.

How is it used?

Nizoral tablets are taken during meals. The daily dose for adults is 200 mg. If necessary, this dose can be doubled.

The duration of treatment depends on the type of disease.

  • With dermatomycosis and systemic mycoses, Nizoral is taken within 1-2 months.
  • Tinea ringworm requires therapy within 10 days.
  • For onychomycosis, treatment can last from 6 months to 1 year.
  • With candidiasis of the skin, the duration of treatment is 2-3 weeks.
  • Vaginal mycosis disappears after 5 days.

To prevent fungal infections, take 400 mg per day.

For children weighing 15 to 30 kg, the dose is usually 100 mg. To prevent fungal or yeast infections, children are prescribed 4 to 8 mg per kilogram of body weight once a day.

Side effects

Kopfschmerzen
Headache

Magenschmerzen
Indigestion,
heartburn

Schwindel
Drowsiness

Schlaflosigkeit
sleep disorders

Schläfrigkeit
Sleepiness

Erregung
excitement

Reizbarkeit
Irritability

Schwäche
Fatigue

Sehstörungen
Visual disturbances

Herzrhythmusstörungen
Palpitations

Verstopfung
Constipation

Übelkeit
Nausea

Durchfall
Diarrhea

Hautausschlag
Itching,
Skin rash

Schwitzen
Sweat

headache
feeling thirsty

Warnings and Precautions

Qtc interval monitoring

Liver function monitoring

Monitoring of adrenal function

Contraception

Possible interactions with other drugs

Concomitant inflammatory diseases/

Alcohol

Other trade names

Terzolin Ket Ketozolin Fungoral Lur Ninazol

Contraindications

Hypersensitivity to the ingredients

Pregnancy

Lactation

Concomitant use with certain drugs

(see section "Interactions")

Liver diseases

Congenital or demonstrated acquired Qtc prolongation

Pregnancy

Avoid during pregnancy

Alcohol

Alcohol consumption should be avoided

What happens if you miss the dose?

You can make up for the missed application during the day and continue to use the dose prescribed by your doctor as usual on the following day.

Overdose

If you suspect an overdose, contact a doctor immediately.

Interactions

There is a risk of significant interactions. Therefore, medical supervision is recommended.

Nizoral interacts with the following drugs: cyclosporine (Gengraf, Sandimmun, Neoral); paracetamol (Tylenol); digoxin (digitalis, lanoxin); Methylprednisolone (Medrol), tacrolimus (Prograf), loratadine (Alavert, Claritin, Tavist ND), rifampin (Rifadin, Rifater, Rifamate, Rimactane), phenytoin (Dilantin), oral antidrugs, tranquilizers such as midazolam, blood thinners such as warfarin (Coumadin), methotrexate (Rheumatrex, Trexall), cancer drugs, birth control pills or hormone replacement therapy, cholesterol drugs such as niacin (Advicor), atorvastatin (Lipitor), lovastatin (Altocor, Mevacor), simvastatin (Zocor), and other drugs used to treat HIV or AIDS.

Unwanted reactions

Nausea

Vomit

Itching

Skin rash

Headache

Dizziness

Impotence

Food

The effect of the drug is influenced by the food.

Always take Nizoral tablets with food as this will help your body use the medicine.

Storage

Keep this medicine out of the sight and reach of children.

Store the medicine at normal room temperature.

Frequently Asked Questions

What are Nizoral tablets used for?

Nizoral can be used for fungal infections of the skin such as ringworm, skin fungus caused by microsporia and infections caused by yeasts.

Can you buy Nizoral tablets over the counter?

Nizoral tablets require a prescription.

In what dosage forms can you buy Nizoral?

Nizoral is available in the form of tablets, cream and shampoo.

How do you know the active ingredient in Nizoral?

The active substance is called ketoconazole.

What is Nizoral?

Nizoral is an antifungal antibiotic used to treat severe fungal or yeast infections. Nizoral kills sensitive fungi by inhibiting the formation of the fungal cell membrane.

The active ingredient in Nizoral is called ketonazole. Nizoral is available in the form of oral tablets, skin cream and shampoo. The tablet is usually taken once a day for a week or more. The cream is applied once or twice a day for 2 to 4 weeks. The shampoo is used twice a week. Treatment with shampoo usually lasts 4 weeks.

When are Nizoral tablets used?

The oral tablets Nizoral are prescribed for the treatment and prevention of fungal diseases. The areas of application include:

  1. Treatment of stomach or intestinal mucosa affected by fungal infection;
  2. Treatment of chronic candidiasis when local therapy is ineffective;
  3. Treatment of systemic fungal infections (coccidioidomycosis, blastomycosis, chromoblastomycosis, histoplasmosis or paracoccidioidomycosis)
  4. Prevention of fungal diseases during chemotherapy.

Nizoral is also used to treat parasitic fungal infections on the skin that cannot be treated with topical medicines or the active ingredient griseofulvin, or in patients who cannot take griseofulvin.

Off-label, Nizoral tablets are used for drug treatment in life-threatening Cushing's syndrome with the aim of reducing cortisol production.

Taking Nizoral tablets for fungal meningitis is not as effective, since the drug poorly penetrates the blood-brain barrier.

Because there is a risk of serious hepatotoxicity, Nizoral tablets should only be taken if the benefit of treatment outweighs the potential risk.

What is to be considered?

Nizoral tablets are not safe for all patients. Before starting treatment, always tell your doctor the following:

  • if you suffer from allergies;
  • if you are pregnant or breastfeeding;
  • if you have other health problems;
  • if you are currently using another medicine;
  • if you use dietary supplements, vitamins or herbal products of any kind.

Nizoral tablets can cause serious side effects, including:

1. Liver problems (liver toxicity). There is a risk of serious liver problems that can lead to death or the need for a liver transplant. See your doctor if you have any of the following symptoms after taking it:

  • loss of appetite or weight loss (anorexia)
  • vomiting or nausea
  • fatigue
  • stomach pain
  • dark urine or light-colored stools
  • jaundice
  • fever or skin rash

2. QT interval prolongation. This prolongation can cause irregular heartbeats, which can be life-threatening. This is possible when Nizoral tablet form is taken at the same time as certain drugs such as quinidine, dofetilide, pimozide, cisapride, disopyramide, methadone, ranolazine and dronedarone. Talk to your doctor about other medicines you are taking before you start taking them. Tell your doctor right away if you feel faint, light-headed, or dizzy, or if your heart is beating irregularly or rapidly. This can talk about QT interval prolongation.

3. Serious heart problems. Contact your doctor if you experience heart palpitations, loss of breath, or dizziness.

Alcohol should be avoided during treatment with Nizoral tablets as alcohol consumption can increase the risk of serious liver problems.

If allergic reactions occur, you should consult a doctor immediately. Symptoms that may indicate an allergic reaction include skin rashes, hives, facial swelling, swollen hands and feet, difficulty breathing, and difficulty swallowing.

Do not combine Nizoral with other antifungal drugs.

Where to buy Nizoral tablets?

Nizoral is available in every pharmacy in Britain. It is also available online. Please note that this drug is subject to prescription in Britain. When you buy Nizoral tablets online, choose a reputable online pharmacy that you trust. Our portal for pharmacy and medicine comparison is used to find a good pharmacy and an affordable price. Use the search box to find the drug you need.

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Buy Nizoral Tablets Online

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Prefer cream rather than pills.

29.04.2022

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