Buy Nizoral Cream

2 %

Available in: 0 Pharmacy(s)

Instructions for use Nizoral Creme



Bioavailability: varies

Protein binding: ≥ 80%

Metabolism: Liver


Half-life: 2 hours during the first 10 hours and 8 hours thereafter

Excretion: Biliary

CAS number: 65277-42-1

PubChem-CID: 3823

UNII: R9400W927I

KEGG: D00351

Molar mass: 531,43 g·mol−1

How does it work?

Nizoral cream contains the active ingredient ketoconazole. Ketoconazole kills fungus and yeast and helps clear the infection. This cream can be prescribed to get rid of a number of different types of fungal and yeast infections.

How is it used?

Nicoral Cream is applied locally. For the treatment of skin candidiasis, skin fungus, groin fungus and pityriasis versicolor, the cream should be applied to the affected skin once a day. With seborrheic dermatitis, the preparation is applied to the affected area once or twice a day, depending on the severity of the lesion. Treatment should be continued for a sufficient period of time, at least a few days after all symptoms of the disease have disappeared. For pityriasis versicolor and yeast infections, the usual duration of treatment is 2-3 weeks. Athlete's foot should be treated for 4-6 weeks. The usual duration of treatment for seborrheic dermatitis is 2-4 weeks.

Side effects

Skin redness,
Skin rash,
Skin flaking or peeling,
Dry skin

water retention

Contact dermatitis

Warnings and Precautions

Caution if you have a history of certain medical conditions

In the case of asthma and allergies in the past, the cream can lead to allergic-like reactions.

Children and young people

The use and safety of this cream in children and adolescents has not yet been tested.

Other trade names

Terzolin Ninazol Fungoral


Hypersensitivity to the ingredients


Not safe


Alcohol consumption increases the risk of complications

Simultaneous alcohol consumption can lead to intolerance reactions

What happens if you miss the dose?

No data available


The skin can be cool and sweaty or hot and dry.

Excessive use or application to the skin more frequently than recommended can cause reddening of the skin (erythema), water retention in the skin (edema) and burning sensation


Interactions are unlikely or not significant

Unwanted reactions

Skin rash



Food does not affect the effects of the drug.


Keep this medicine out of the sight and reach of children.

Store the medicine at normal room temperature.

Frequently Asked Questions

What is Nizoral cream?

NIZORAL Creme is a local remedy for treating external skin infections caused by fungi or yeasts. It is used for inflammation in certain parts of the body, such as the chest, hands, feet, back, or groin.

Can you buy Nizoral cream over the counter?

Yes. You can buy Nizoral cream without a prescription in any pharmacy. However, it is worth speaking to a doctor first. There are certain price differences from pharmacy to pharmacy. Thanks to our price comparison you will find the best offers.

What is Nizoral cream?

Nizoral Cream belongs to the group of antimyotics and effectively fights parasitic dimorphic fungi and yeast fungi, acts against dermatophytes and eumycota. The cream is used to treat skin diseases caused by a fungal infection. The active substance of the antifungal drug ketoconazole disrupts the synthesis of the membrane components of fungi, which leads to the death of the pathogen. The drug also affects the activity of gram-positive bacteria (streptococci and staphylococci).

After applying Nizoral 2% cream, the active substance ketoconazole quickly penetrates deep into the affected tissue and acts at the cellular level. But at the same time, ketoconazole is not absorbed into the systemic circulation. Therefore, the medicine can be used for a long time (up to six months or more).

Who is Nizoral Cream prescribed for?

The use of the drug is indicated for the treatment of fungal infections of the skin, scalp and nails. Nizoral 2% Cream is prescribed to patients with pityriasis versicolor, dermatophytosis, skin candidiasis, folliculitis and seborrheic dermatitis caused by Malassezia yeast.

What are the side effects of Nizoral cream?

The safety of Nizoral 2 percent Cream was evaluated in 1079 patients in 30 clinical studies in which this cream was applied topically to the skin.

Based on the results obtained, the most common adverse reactions are application site itching (2%), skin burning sensation (1.9%) and application site erythema (1%).

Uncommon side effects are:

  • increased sensitivity
  • contact dermatitis
  • skin rash
  • skin flaking
  • bleeding
  • discomfort
  • skin dryness
  • inflammation
  • skin irritation

Undesirable effects on the part of the central nervous system and the peripheral nervous system are headache, dizziness, paresthesia, photophobia, increased intracranial pressure.

Digestive side effects include nausea, vomiting, diarrhea.

Thrombocytopenia can occur on the part of the hematopoietic system.

The reproductive system can react to the cream in the form of gynecomastia, oligospermia and menstrual disorders.

Is Nizoral Cream Safe During Pregnancy and Breastfeeding?

Although ketoconazole does not penetrate the skin when using Nizoral cream, adequate and well-controlled studies in pregnant and lactating women have not been conducted.

No plasma levels of ketoconazole were detected after application of Nizoral 2 percent cream to the skin of non-pregnant women.

The risks associated with using cream during pregnancy are unknown.

There is no evidence that Nizoral Cream 2% can be dangerous in pregnant women and while breastfeeding.

During pregnancy and breastfeeding, Nizoral 2% cream is used only if the intended benefit for the mother, after consulting a doctor, outweighs the potential risk to the fetus and child.

Important information about Nizoral Cream

The cream is only suitable for local therapy.

Nizoral 2 percent Cream is not suitable for children and adolescents under 18 years of age.

It is important to use this cream for three or four days after the symptoms of the infection have disappeared. This ensures complete treatment and prevention of infection.

If the infection has not gone away after four weeks of therapy, you should consult your doctor.

Nizoral 2% Cream contains propylene glycol which may cause skin irritation.

The drug also contains 1-hexadecanol and 1-octadecanol, which can cause skin reactions such as contact dermatitis.

Can Nizoral Сream be used with other medicines?

Yes. Nizoral Cream 2 Percent is not absorbed through the skin into the bloodstream in significant amounts and is therefore not expected to affect other medicines.

If you use other creams, ointments or lotions (including moisturizers or cosmetics) on the same skin area, you should preferably not apply them at the same time as Ketoconazole 2% Cream. This is because they could dilute the medicine and make it less effective at treating the infection. Always allow about 30 minutes between applying different products to the same area of skin to allow them to be absorbed.

When using a steroid cream, do not use both creams at the same time. For example, you can apply steroid cream in the morning and Nizoral 2% cream in the evening.


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