Patent: Patent expired
Producer: Aristo Pharma GmbH, Aurobindo Pharma GmbH, Heumann Pharma GmbH & Co. Generica KG, neuraxpharm Arzneimittel GmbH
Dosage: 100mg, 200mg
Dosage form: tablet
Unit of measurement: mg
Active ingredient: modafinil
Onset of action: 30-60 minutes
Duration of action:
Other names: (RS)-2-[(Diphenylmethyl)sulfinyl]acetamid (IUPAC)
Protein binding: ≥ 60%
Half-life: 15 hours
CAS number: 68693-11-8
Drug Bank: DB00745
Molar mass: 273,35 g·mol−1
Modafinil belongs to a class of drugs called stimulants that keep you awake. Like amphetamines, modafinil promotes alertness by stimulating the brain. Modafinil's exact mechanism of action is unknown. It is thought to increase the amount of dopamine in the brain by decreasing the reuptake of dopamine in nerves.
Modafinil helps against excessive daytime sleepiness in narcolepsy without causing serious side effects. The half-life is 10 to 12 hours.
Always take Modafinil exactly as your doctor has told you. Modafinil tablets should be swallowed whole with water.
The usual standard dose for adults is 200 mg per day. The daily dose can be taken all at once (in the morning) or divided into two doses per day (100 mg in the morning and 100 mg at noon). If necessary, the daily dose can be increased up to 400 mg by the doctor.
For elderly patients, as well as adult patients with serious kidney and liver diseases, the daily dose is 100 milligrams.
Be careful if you have heart disease
Hypersensitivity to the ingredients
Untreated or insufficiently treated high blood pressure
Alcohol consumption should be avoided
Do not take a double dose to make up for a forgotten dose. For the next dose, do not take more than the usual recommended amount.
If you take more of this medicine than you should, it could cause serious side effects.
There is a risk of serious interactions. Therefore, regular medical monitoring is required.
Food does not affect the effects of the drug.
This medicinal product does not require special storage conditions.
What is Modafinil?
In what dosage can you buy Modafinil?
How long does Modafinil work?
Can I Consume Alcohol While Taking Modafinil?
Modafinil is a prescription drug used to treat excessive sleepiness caused by narcolepsy. By 2011, it was also approved throughout Britain for the treatment of excessive sleepiness in obstructive sleep apnea syndrome or chronic shift worker syndrome.
Off-label, this drug is used for chronic fatigue syndrome, ADHD, depression or eating disorders.
Modafinil was first developed in France in the early 1990s. When the patent expired in 2011, there are its generics on the market, such as Modalert, Modvigil, Vilafinil, etc.
Since Modafinil was first introduced, it has been one of the most commonly prescribed medications for excessive sleepiness associated with narcolepsy. The reason for this is the lack of serious side effects. For example, unlike amphetamines, modafinil does not cause a sympathomimetic effect and has a substantially low potential for abuse.
Modafinil is considered a well-tolerated drug. According to recent studies, however, it can lead to abuse and addiction. In addition, prolonged excessive sleepiness leads to stress reactions and compromises the immune system.
In most European countries, modafinil requires a prescription. Britain, Austria and Switzerland are no exception. Here you will not find a classic pharmacy that sells modafinil without a prescription.
Modafinil is readily available over the internet without a prescription. However, online pharmacies located in non-prescription countries can sell modafinil over the counter to anyone who wants it.
Most modafil-containing medicines sold online are exported from India. This is explained by the fact that the laws regarding the sale of medicines in this country are very generous.
In Britain, Austria, Switzerland, the USA and in many other countries you cannot buy modafinil without a prescription because it is subject to prescription. Adrafinil-containing drugs, on the other hand, are over-the-counter in some countries. Adrafinil is a prodrug that only becomes effective when it is metabolized to Modafinil.
Modafinil can cause mild or serious side effects. Common side effects include
Skin rashes may occur during use. If this side effect occurs, treatment should be discontinued and a doctor consulted.
The drug should be taken sporadically. If this drug is used long-term, there is a risk of dependence. Tolerance to the active substance can also develop. For this reason, patients take an increased dose to achieve an effect.
To prevent the development of tolerance, the preparation should be taken once a week. This means that the body continues to react "sensitively" to the active substance. If modafinil needs to be taken more frequently for various reasons, it should not be used more than three times a week.
Armodafinil, sold under the brand name Nuvigil, is a newer drug compared to modafinil. It was approved in 2007 as the (R)-enantiomer of modafinil. The enantiomers are the molecules that are mirror images of each other (think of your left and right hands as examples). In this way, armodafinil has a slightly different chemical structure than modafinil.
Armodafinil may have a longer half-life compared to modafinil. In some cases, Armodafinil can be considered a stronger drug with better wakefulness effects. While both drugs can have the similar side effects, some side effects may be more common with one drug than the other.
The difference is also in the standard dose. While armodafinil should be taken in a daily dose of 150 mg, the daily dose of modafinil is 200 mg.
Modafinil comes in 100mg or 200mg tablet form. Armodafinil is also available as tablets. Available dosages are 50mg, 150mg, 200mg and 250mg.
No, these are two different drugs. Modafinil and Ritalin are popular central nervous system stimulants. Both Ritalin and Modafinil have similar effects in the brain, all of which help increase feelings of alertness.
In general, Ritalin is better for increasing dopamine levels, while Modafinil is better for stimulating alertness.
In terms of duration of action, modafinil effects last significantly longer than Ritalin effects.
Individual proofs :
I've been taking modafinil for narcolepsy for 3 years as it works well for me. After taking it, I'm not tired at all and feel powerful. Sometimes I have diarrhea, which really bothers me. That's not good about Modafinil, but other than that it's a very good and effective drug!
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