Patent: Patent expired
Producer: Hoffmann-La Roche
Dosage: 0.5mg, 2mg
Dosage form: tablet
Unit of measurement: mg
Active ingredient: clonazepam
Seizures, Panic disorders, Anxiety disorders, Depressions
Drug class: benzodiazepines
Onset of action: 15-30 minutes
Duration of action: 6-8 hours
Protein binding: ≥ 80%
Metabolites: 7-Aminoclonazepam; 7-Acetaminoclonazepam; 3-Hydroxy Clonazepam
Half-life: 18-60 hours
CAS number: 1622-61-3
Drug Bank: DB01068
Molar mass: 315,71 g·mol−1
This medicine contains the active substance clonazepam, which belongs to the benzodiazepine group. Clonazepam has an inhibitory effect on many structures in the central nervous system. It has an antispasmodic, anxiolytic, sedative and moderately pronounced hypnotic effect, and also reduces skeletal muscle tone. Clonazepam raises the seizure threshold and prevents the onset of generalized seizures.
Klonopin tablets are administered orally. The dosage should be determined individually by the doctor. The usual starting dose for adults is 1 mg per day. The maintenance dose is usually 4-8 mg daily.
For infants and children between the ages of 1 and 5 years, the starting dose should not be more than 250 μg/day. For children aged 5 to 12 years, 500 μg / day is prescribed. Daily maintenance doses for children under the age of 1 year are 0.5-1 mg, between the ages of 1 and 5 years 1-3 mg and between 5 and 12 years 3-6 mg respectively.
For elderly patients, an initial dose of 500 µg should not be exceeded.
Severe liver disorders
Hypersensitivity to the ingredients
Avoid during pregnancy
Alcohol consumption should be avoided
Do not take a double dose to make up for a forgotten dose. For the next dose, do not take more than the usual recommended amount.
If you suspect an overdose, contact a doctor immediately.
There is a risk of significant interactions. Therefore, medical supervision is recommended.
Food does not affect the effects of the drug.
Keep this medicine out of the sight and reach of children.
What is Klonipin for?
Does Klonipin require a prescription?
How does clonazepam work?
Can you buy clonazepam online?
Under what trade names can clonazepam be bought?
Klonopin (active ingredient clonazepam) is a prescription medication used to treat various mental illnesses such as anxiety, panic disorders and depression. Since the drug is also an antispasmodic, it is also prescribed to prevent seizures associated with epilepsy and relieve the symptoms of restless legs syndrome. Although this drug is known as Klonopin® in the US, it is marketed in countries including Great Britain under the trade name Rivotril® by the Swiss company F. Hoffmann-La Roche AG.
Klonopin is assigned to the drug group of benzodiazepines. It changes mood and affects the central nervous system. Biochemical effects on the brain give the drug the ability to affect cognition and behavior. Unfortunately, these properties also lead to the deliberate abuse of this substance.
As with other psychiatric drugs, there are certain risks associated with taking Klonopin. There is a risk of developing chemical dependency through long-term or habitual use. For this reason, the preparation should be used under medical supervision.
Klonipin drug causes drowsiness and muscle weakness and impairs concentration and alertness. These symptoms can last up to the next day and are made worse by alcohol consumption. For this reason, operating machines is not recommended. Alcohol consumption should also be avoided.
You should not suddenly stop taking Klonopin medicine. Stopping a benzodiazepine suddenly can produce withdrawal symptoms such as insomnia or anxiety, sweating, confusion, tremors, irritability, or headaches. Weaning should be gradual. Follow your doctor's instructions.
Some antiepileptic drugs are associated with an increased risk of suicidal thoughts and behavior. It is not known whether clonazepam also has this effect. For this reason, it is very important to seek medical advice if you experience mood swings or suicidal or self-consciousness during the treatment regimen.
As for the side effects, Klonopin drug can cause the drowsiness and impair the cognitive and motor functions. Because of this effect, the drug is not usually recommended for young children or the elderly. Ingestion can also impair REM sleep.
Finally, Klonopin should not be used during pregnancy.
Taking Clonazepam-containing Klonopin at the same time as medicines that have a central nervous system inhibitory effect, such as ethanol or medicines containing ethanol, leads to an increase in the central nervous system inhibitory effect.
In the case of a combination of clonazepam and desipramine, the plasma level of desipramine is reduced.
The effect of muscle relaxants is enhanced with simultaneous use with clonazepam. Concomitant administration with clonazepam reduces the effect of valproate.
When taken at the same time as caffeine, it is possible to reduce the sedative and anxiolytic effects of clonazepam.
When Klonopin is combined with lamotrigine, the plasma concentration of clonazepam decreases. Simultaneous administration with lithium carbonate can lead to the development of neurotoxicity.
With the simultaneous use of clomazepam with primidone, the plasma concentration of primidone increases.
The drug Klonopin also interacts with phenytoin. However, caution is advised as concomitant use increases the plasma level of phenytoin and toxic reactions and concentration disorders may occur.
Phenelzine can cause the headache when combined with Clomazepam.
With simultaneous administration with cimetidine, side effects from the central nervous system increase, but in some patients the frequency of seizures decreased.
Klonopin drug also interacts with tiapride, toremifene and many other drugs and medications. For this reason, you should inform your doctor about all the preparations you are taking or have recently taken.
I lived very well with Klonopin for 3 years, but this year I was allowed to get to know the downsides of such a powerful drug.
I started taking Klonopin 2 years ago and am not considering switching to another drug. I`m sleeping well again. When I fell asleep, I felt abrupt impulses that have now disappeared. I`ve tried coming off Klonopin before but have experienced a lot of withdrawal symptoms. So I`m taking this drug again.
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