Patent: Patent expired
Producer: Sanofi, MEDA Pharma GmbH & Co. KG
Dosage: 3.75mg, 7.5mg
Dosage form: tablet
Unit of measurement: mg
Active ingredient: zopiclone
Application areas:
Sleep disorders
Drug class: hypnotics
Onset of action: 30-60 minutes
Duration of action:
Other names: [(5RS)-6-(5-Chlorpyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl](4-methylpiperazin-1-carboxylat)
Bioavailability: 50-100%
ATC-Code: N05CF01
Protein binding: ≥ 50%
Metabolism: Liver
Half-life: 5 hours
Excretion: Urine
CAS number: 43200-80-2
PubChem-CID: 5735
Drug Bank: DB01198
ChemSpider: 5533
UNII: 03A5ORL08Q
KEGG: D01372
ChEBI: CHEBI:32315
ChEMBL: ChEMBL135400
ECHA-InfoCard: 100.051.018
Formula: C17H17ClN6O3
Molar mass: 388.81 g·mol−1
The active ingredient is called zopiclone. It belongs to non-benzodiazepines from the group of anxiolytics. Zopiclone increases the activity of a neurotransmitter called GABA in the brain. Neurotransmitters are natural body chemicals that act as messengers between nerve cells. GABA is a neurotransmitter that exerts the effects of a natural "nerve calming" agent. It induces sleep, reduces anxiety and relaxes muscles.
The active substance zopiclone reduces sleep latency and the number of nocturnal awakenings, as well as prolongs sleep duration.
Before starting the intake, the patient should consult a doctor. The dosage is between 3.75 mg and 7 mg. For the elderly, the maximum dosage is 5 mg. This medication should be taken as directed by the doctor in charge to ensure its effectiveness.
The treatment should last from 7 to 10 days, depending on the case. If you continue treatment with Imovane sleeping tablets, there is a high risk of dependence. You should also talk to your doctor before you stop taking it.
Tolerance development
Mood swings and depression
Withdrawal symptoms
Hypersensitivity to the ingredients
Severe muscle weakness
Severe breathing disorders
Sleep apnea syndrome
Severe liver damage
This medicine should not be used in children and adolescents under 18 years of age.
Avoid during pregnancy
Alcohol consumption increases the side effects of medication
Do not apply a double dose if you have forgotten the previous application, but continue the application as before.
Serious side effects can occur after taking excessively high doses. If you experience severe side effects, seek medical help immediately.
There is a risk of serious interactions. Therefore, regular medical monitoring is required.
Drowsiness
Dizziness
Food does not affect the effects of the drug.
Keep this medicine out of the sight and reach of children.
Do not store above 25°C.
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Imovane is a prescription sleep medication for the treatment of major insomnia in people 18 years and older. The active ingredient in Imovane Zopiclone belongs to a class of hypnotics and is used for short-term use. It has been approved since 1994. Imovane is classified as a Z-drug (new generation sedative).
In general, it is used in cases of difficulty falling asleep, difficulty staying asleep, unrefreshing sleep and early morning awakenings. It helps you fall asleep faster and stay asleep throughout the night.
This sleep aid is available in 3.75 and 7.5 mg film-coated tablets. Imovane price depends on dosage and package size, the more tablets you buy, the cheaper Imovane price.
The sleeping pills Imovane (Zopiclon) require a prescription. They may only be used after consultation with the doctor treating you. This is explained by the fact that all Z-Drugs should only be taken when clearly indicated, in the smallest possible dosage and over the shortest possible period of time.
If you want to buy Imovane without a prescription, you should use the services of an online vendor. However, there is a risk for the fakes.
When prescribing Imovane sleeping tablets, it should be borne in mind that treatment with these sleeping pills (even in therapeutic doses) can lead to the development of physical and psychological dependence. The risk of dependence is minimal if the treatment lasts no more than 4 weeks.
The risk of addiction or abuse can be increased by:
If physical dependence develops, stopping treatment suddenly can cause withdrawal symptoms. Such withdrawal symptoms include headaches, muscle aches, extreme restlessness, tension, anxiety, confusion, and irritability. In severe cases, the following symptoms may occur: depersonalization, derealization, hyperacusis, hypersensitivity to light or noise, numbness, tingling, hallucinations or epileptic seizures.
Some medicines are not suitable for people with certain medical conditions. For this reason, before taking Imovane sleeping tablets, it is important to tell your doctor about the following:
There is a risk of anterograde amnesia, particularly when sleep is interrupted or after a long interval between taking Imovane and bedtime. To reduce this risk, you need to take a pill immediately before bedtime.The drug is not indicated for the treatment of depression and can even mask its symptoms.
In some cases, these sleeping pills can cause behavior changes, which sometimes include worsening symptoms of depression. In this case, contact your doctor immediately. Thoughts of suicide or self-harm are also part of behavioral changes.
Because of possible drug interactions, your doctor or pharmacist should know which medicines you are already taking. Below are some of the interactions provided.
Painkillers: If you need to take a painkiller with Imovane, it can be paracetamol or ibuprofen. Avoid codeine and dihydrocodeine.
Opioids. If you are on treatment with an opioid, such as a strong pain reliever such as morphine, tramadol tablets, dihydrocodeine or fentanyl, a cough medicine such as codeine or pholcodine, or an addiction treatment drug such as methadone, taking Imovane may also be prone to depression sleep so that you cannot breathe properly or have difficulty getting up.
Medicines for infections: co-administration can increase the amount of zopiclone in the blood, which can increase the sedative effect and the risk of side effects.
If you are taking clarithromycin, ketoconazole, erythromycin, HIV protease inhibitors (such as ritonavir) or itraconazole, Imovane dose reduction is required.
Other medicines that may make you drowsy: the following medicines increase the sedative effects of Imovane (zopiclone) and must not be combined:
The effectiveness of sleeping pills Imovane 7 5 is reduced when taken concomitantly with carbamazepine, phenytoin, phenobarbital, rifampicin, or St. John's wort.
Strong sleeping pills with great effects. Have been taking Imovane for insomnia for 3 weeks. I got along great with these sleeping pills.
15.05.2022
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