Patent: Patent expired
Producer: Pfizer Pharma GmbH
Dosage: 37.5mg, 75mg, 150mg
Dosage form: capsule
Unit of measurement: mg
Active ingredient: venlafaxine
Application areas:
Depressions, Anxiety disorders
Drug class:
Onset of action:
Duration of action:
Bioavailability: 0-50%
ATC-Code: N06AX16
Protein binding: ≥ 20%
Metabolism: Liver
Metabolites:
Half-life: 5 hours
Excretion: Kidneys
CAS number: 93413-69-5
PubChem-CID: 5656
Drug Bank: DB00285
ChemSpider: 5454
KEGG: D08670
ChEBI: CHEBI:9943
ECHA-InfoCard: 100.122.418
Formula: C17H27NO2
Molar mass: 277,40 g·mol−1
Effexor inhibits the reuptake of noradrenaline and serotonin, which means that both messenger substances remain active and therefore effective for longer. This achieves the mood-enhancing and drive-enhancing effects.
The recommended starting dose for adults with depression, generalized anxiety disorder and social phobia is venlafaxine 75 mg per day. In some cases, treatment can be started at 37.5 mg to allow the body to adjust to the drug.
The recommended starting dose for patients with panic disorder is 35 mg per day.
Depending on the need and tolerability of venlafaxine, the dose can be gradually increased by the doctor every four days to 150 mg per day and then up to 225 mg per day.
The maximum recommended dose for moderately depressed patients is 225 mg per day.
Possible interactions with other drugs
Dizzy spells in the past
Hypersensitivity to the ingredients
Simultaneous administration with MAO inhibitors
Not safe
Alcohol consumption should be avoided
If you miss a dose, you must make up for it as soon as possible. However, you must not take more than your total daily dose in any 24-hour period. double
If you suspect an overdose, contact a doctor immediately.
There is a risk of significant interactions. Therefore, medical supervision is recommended.
Seizure
Increased coughing
Stomach pain
Itching
The effect of the drug is influenced by the food.
Effexor should be taken with meals.
Keep this medicine out of the sight and reach of children.
This medicinal product does not require special storage conditions.
What is Effexor for?
Can children take Effexor?
What is the recommended dose of Effexor?
How long does it take for Effexor to reach its full effectiveness?
Is there a generic version of Effexor?
Can you buy Effexor without a prescription?
Venlafaxine hydrochloride, marketed as Effexor or Efexor, is a selective serotonin-norepinephrine reuptake inhibitor used to treat depression, panic attacks, and panic disorder. It blocks the reuptake of serotonin and norepinephrine, two chemicals in the brain that transmit nerve signals. Effexor was the first antidepressant from this group, first manufactured by Wyeth Pharmaceuticals.
In 1997, an extended-release alternative to Effexor called Effexor XR appeared on the market.
Wyeth Pharmaceuticals Inc. made both drugs until Pfizer bought the company in 2009. Nowadays, the giant Pfizer only markets the Effexor XR extended-release capsules. In Europe, this medicine is known as Efexor ER.
The patent for Effexor expired in December 2008, and since then numerous generics have come onto the market.
You will not find the preparation Effexor in the on-site pharmacies. There are numerous venlafaxine generics on the market throughout Britain. If you would like to try Effexor, you can find it from online suppliers on the Internet. The price varies depending on the online pharmacy.
Venlafaxine is available in the form of tablets or capsules of 37.5 mg and 75 mg, as well as prolonged-release capsules of 37.5 mg, 75 mg, 150 mg, 225 mg and 300 mg.
For most people, it is safe to take Effexor medication long-term. However, some patients may develop sexual disorders such as B. Erection problems or low sexual desire.
In some cases, these problems can continue even after stopping the drug. Talk to your doctor if you're concerned about this.
Otherwise, taking Efexor for many months and years doesn't seem to have any long-term harm.
Whether a patient should take Efexor for life depends on whether they have had more than 3 depressive episodes. Then it can justify lifelong administration and of course in consultation with the psychiatrist. From clinical experience there is no evidence of serious long-term damage.
It is desirable to start treatment with a low dose, and then gradually increase it. Never stop treatment with Effexor suddenly. It should be noted that withdrawal symptoms can also occur with gradual weaning. Therefore, discontinuation should be a lie under medical supervision.
Withdrawal symptoms include gastrointestinal upset, bizarre dreams, dizziness, nausea, headache, paresthesia, mood swings, etc.
Among the most undesirable effects of venlafaxine are those related to sexual dysfunction such as lack of interest in sex, difficulty arousing, and inability to achieve orgasm. Other side effects include nausea, dry mouth, constipation and sweating.
However, the more serious side effects of Effexor affect pregnant or breastfeeding women, children, teenagers, and young adults. Efexor is not approved for use in children, pregnant and breastfeeding women.
Newborns whose mothers took the drug in the third trimester of pregnancy can have serious problems immediately after birth, including seizures and breathing problems. The drug can pass into breast milk and harm the baby.
There is also a risk for suicidal thoughts and behavior in patients under the age of 25.
Efexor interacts with drugs that affect serotonin levels, such as B. other antidepressants, linezolid, lithium, tramadol and St. John's wort. Co-administration with any of these drugs can develop serotonin syndrome, which increases blood pressure, heart rate, and body temperature.
Tell your doctor about all prescription and over-the-counter medications and supplements you have taken or plan to take, including aspirin, medications for migraines, amphetamines, antipsychotics, and blood thinners. Concomitant use with blood thinners or nonsteroidal anti-inflammatory drugs such as Advil and Motrin may increase the risk of blood system side effects.
It is contraindicated to administer Effexor within two weeks of taking an MAOI. An MAOI must not be taken within a week of stopping Efexor.
Alcohol consumption is discouraged while taking the drug.
itemizations
I have been taking Effexor 75 mg for depression and anxiety for many years. At first it had a very good effect. Now after all these years I have the impression that Effexor is not that effective anymore. My depression and anxiety are less severe and more intense, but they`re coming back. As for side effects, I have profuse sweating and nausea.
25.04.2022
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