Buy Cymbalta

What kind of medicine is Cymbalta?

Cymbalta is a prescription antidepressant. It contains the active substance duloxetine, which belongs to the group of selective serotonin-norepinephrine reuptake inhibitors.

Cymbalta is approved by the EMA to treat a variety of conditions. It is suitable for adults suffering from depressive episodes; generalized anxiety disorder or pain associated with diabetic neuropathy.

It is also widely applied in pediatrics. This antidepressant can be used to treat generalized anxiety disorder in children over the age of 7 and fibromyalgia in children over the age of 13.
Compared to other drugs from the serotonin-norepinephrine reuptake inhibitor group, Cymbalta does not have a major impact on blood pressure changes. However, it may take several weeks before you feel the full effect of the medicine on your mood.

Cymbalta is available as enteric-coated hard capsules. The capsules are available in 2 strengths: 30 milligrams and 60 milligrams. Cymbalta is also available as a generic drug called duloxetine.

Cymbalta price at a glance

The price of Cymbalta depends on several factors. The manufacturer plays a role here. Since Cymbalta is generic today, it costs less than the brand name. The price is related to the dosage and package size. The more tablets in a pack, the lower the price.

Table: Cymbalta price 30 mg vs 60 mg

How long do Cymbalta side effects last?

How long this or that side effect of Cymbalta lasts depends on the side effect itself. Also, your risk of certain side effects may be higher when you first start taking the drug. For example, the risk of suicidal thoughts or behavior may be highest in the first few months after taking Cymbalta or after a dose change. However, these thoughts or behaviors can occur at any time while you are taking Cymbalta.

The risk of orthostatic hypotension is also highest in the first week after taking Cymbalta. Some side effects may go away once the drug is stopped. The other side effects like liver failure may not go away after stopping the drug. If you have the questions about the risk of Cymbalta side effects, consult your doctor or pharmacist.

Can you combine Cymbalta with alcohol?

Taking Cymbalta is associated with the risk of liver damage. And drinking alcohol while on this intake can increase this risk. Therefore, alcohol consumption should be avoided or limited during treatment with Cymbalta.

Consult your doctor immediately if you have any of the following symptoms as these may be symptoms of liver damage:

• chills;
• fever;
• joint pain or swelling;
• unusual bleeding or bruising;
• excessive tiredness or weakness;
• rash or itching;
• nausea;
• vomit;
• loss of appetite;
• dark urine;
• jaundice.

Does Cymbalta interact with other drugs and medicines?

Because of drug interactions, caution should be exercised when combining Cymbalta with other drugs.

Cymbalta should not be taken at the same time as or within 2 weeks of taking MAOIs. These include tranylcypromine (Jatrosom), rasagiline (Azilect), and selegiline (Movergan, Antiparkin).

Such drugs as cimetidine (CimLich), ciprofloxacin (Ciloxan), fluoxetine (Prozac, Generic Fluoxetine), fluvoxamine (Fevarin, Luvox), paroxetine (Allenopar, Paroxalone) may increase plasma levels and affect the effects of duloxetine.

Rarely, there is an increased risk of serotonin syndrome when Cymbalta is used concomitantly with other medicines that increase serotonin. Such drugs include other antidepressants, anti-migraine drugs from the triptan group (e.g. Imigran) and some painkillers (e.g. Tramadol, Ultram), antibiotic Zyvoxide and amphetamines.

Co-administration with other drugs that can cause bleeding (e.g. ibuprofen, warfarin and aspirin) increases the effects of these drugs.

What happens if you just stop using Cymblta?

Abrupt discontinuation of treatment with Cymblta must be avoided as this can trigger pronounced discontinuation phenomena (anxiety, tinnitus, agitation, confusion). Discontinuation should generally be gradual (over 2 weeks).

Resources

1. What Other Medications May Interact With Duloxetine? National Alliance on Mental Illness. URL: https://www.nami.org/
2. Settle EC "Antidepressant drugs: disturbing and potentially dangerous adverse effects." J Clin Psychiatry 59 Suppl 16 (1998): 25-30
3. Package leaflet of CYMBALTA 60 mg gastro-resistant capsules, hard