Patent: Patent expired
Producer: RIEMSER Pharma GmbH, Pfizer Pharma GmbH
Dosage: 25mg, 50mg, 100mg
Dosage form: coated pill
Unit of measurement: mg
Active ingredient: spironolactone
Primary hyperaldosteronism, Swelling
Drug class: antimineralocorticoid
Onset of action:
Duration of action:
Other names: 7α-Acetylthio-3-oxo-17α-pregn-4-en-21,17β-carbolacton
Protein binding: ≥ 80%
Metabolites: 7α-TS, 7α-TMS, 6β-OH-7α-TMS
Half-life: 1.4 hours
CAS number: 52-01-7
Drug Bank: DB00421
Molar mass: 416,57 g·mol−1
The action of Aldactone pills is aimed at inhibiting the action of aldosterone. Too much aldosterone in the body causes the kidneys to retain more sodium and water, while too much potassium is excreted from the body.
Aldactone stimulates urination by increasing the elimination of excess water and salt in the body. It also lowers high arterial blood pressure. It can be used alone or with other diuretics. It improves the effectiveness of other antihypertensive medicines.
Aldactone also exerts an anti-androgenic effect by acting against male sex hormones. For this reason, Aldactone is used off-label in the treatment of female hirsutism. It works by reducing hair growth. The safety of Aldactone pills for the treatment of hirsutism in women of childbearing potential has not been established by specific studies. Your doctor may recommend combined use with oral contraceptives to ensure both regular menstrual cycles and adequate contraception.
Aldactone is taken orally, whole and with sufficient liquid. The daily dose depends on several factors. The following plays a role here:
For adults, the usual starting dose is 100-200 mg daily for 3-6 days. If necessary, the daily dose can be increased to 400 mg spironolactone.
The maintenance dose is between 50-200 mg spironolactone and can be taken daily, every 2nd or every 3rd day as required.
For children, the recommended starting dose is 3 mg/kg body weight daily for five days. If necessary, the dose is increased to 9 mg/kg body weight daily until the clinical effect occurs. The duration of treatment for children is up to 30 days.
Possible interactions with other drugs
Regular checks of the mineral balance and the examination of certain blood values
Hypersensitivity to the ingredients
Severe kidney disorders
Concomitant use with certain drugs
Excess potassium in the blood
Severely restricted urine production
Acute renal failure
Avoid during pregnancy
Alcohol consumption should be avoided
If you miss a dose, do not take twice as much the next time, but take it as described in the dosage instructions or as instructed by your doctor
If you suspect an overdose, contact a doctor immediately.
There is a risk of significant interactions. Therefore, medical supervision is recommended.
Severe changes in blood count
Decrease in blood platelets
The effect of the drug is influenced by the food.
This medicinal product does not require special storage conditions.
What is Aldactone?
Can Aldactone be taken for high blood pressure?
What foods should you avoid while taking Aldactone pills?
When is the best time to take Aldactone pills?
What is Aldactone price?
Can I buy Aldactone over the counter?
How to buy Aldactone online cheaply?
Aldactone (active ingredient Spironolactone) is a diuretic that is able to increase urination. This is a brand-name prescription drug that contains the active ingredient spironolactone and belongs to a group of drugs called aldosterone antagonists or potassium-sparing diuretics.
Aldactone pills are used to treat primary hyperaldosteronism unless surgery to the system is indicated. Primary hyperaldosteronism is a condition characterized by increased secretion of the hormone aldosterone by a tumor in the adrenal gland.
The second area of application is an accumulation of water in the tissue (edema) and/or in the abdominal cavity (e.g. ascites) in diseases associated with secondary hyperaldosteronism.
Aldactone is also FDA approved to treat high blood pressure.
In addition to the uses listed above, Aldactone pills can be used off-label for other purposes. It can also be used to treat acne, hair loss, ovarian syndrome and hirsutism.
The drug Aldactone with the active ingredient spironolactone is commercially available as coated tablets and hard capsules. Coated tablets are available in 3 strengths: 25 milligrams, 50 milligrams and 100 milligrams. As hard capsules, Aldactone is only available in one dosage (100mg).
On the pharmaceutical market there is also the preparation Aldactone® 10ml canrenoate, which is produced by the RIEMSER company and is available as an infection solution. Unlike coated tablets and hard capsules, the infection solution contains the other active ingredient, namely potassium canrenoate.
The price of Aldactone depends on a dosage, a package size and a supplier. It also plays a role here whether you buy Aldactone brand or a generic.
To buy the drug cheaply, compare the prices from various online suppliers who have Aldactone in their range.
Aldactone 25 mg prices start from €13.73 for 50 pills and from €16.31 for 100 pills. Buy generic, pay less.
Aldactone is capable of causing both mild and serious side effects.
Mild adverse effects include dizziness, headache, confusion, itching, drowsiness, menstrual cramps, diarrhea, sexual dysfunction, abdominal cramps, vomiting, and nausea.
Most of these side effects usually go away within a few days or weeks. However, if they become more severe or do not go away, one should see a doctor.
Serious side effects are not common, but are possible. These include gynecomastia, electrolyte imbalances, allergic reactions, and skin conditions like Stevens-Johnson syndrome.
You may feel dizzy for the first few days. Avoid driving and operating machines.
Aldactone can increase the level of potassium in your blood. Avoid taking potassium supplements and foods high in potassium, such as bananas and broccoli.
Your kidney function and the amount of potassium in your blood should be checked regularly by your doctor while you are being treated with this medicine.
If you experience dizziness, vomiting, diarrhea, fast or irregular heartbeat, swelling in your feet, or trouble breathing, tell your doctor right away.
The coated pills can cause chest pain/swelling, menstrual irregularities and sexual problems in patients.
Tell your doctor about all medicines you are taking or using.
Aldactone pills interact with a number of drugs such as:
The effect of Aldactone 25 mg is effective and the side effects of drowsiness and a slight headache are not a problem for me. Aldactone 25 price is satisfactory.
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