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There is a risk of serious interactions. Therefore, regular medical monitoring is required.

There is a risk of significant interactions. Therefore, medical supervision is recommended.

• Hypersensitivity to the ingredients
• Taking Riociguat
• Vision loss due to nonarteritic anterior ischemic optic neuropathy (NAION)
• Intake of nitrates
• Low blood pressure
• Kidney diseases

• Heart problems such as a heart attack, irregular heartbeat, angina, chest pain, aortic stenosis, or heart failure
• Hypersensitivity to the ingredients
• Epilepsy
• Severe liver disorders
• Severe kidney disorders
• Fluctuating blood pressure
• Blood clotting disorders

• Serious side effects can occur after taking excessively high doses. If you experience severe side effects, seek medical help immediately.

• Overdose can cause headaches, nasal congestion, and blurred vision.

• Pfizer Pharma GmbH

• Ajanta Pharma Ltd.

• Particular caution in patients with impaired renal function
• Caution in severe liver dysfunction
• Cardiovascular risk factors
• Concomitant use of other PDE5 inhibitors or other treatments for erectile dysfunction
• Priapism
• Effects on eyesight
• Concomitant use of ritonavir
• Simultaneous use of alpha blockers
• Effects on blood clotting

• Priapism
• Be careful if you have heart disease
• Visual disturbances
• Caution when taking or using certain medicines

• Headache
• Facial flushing
• Stuffy nose
• Dizziness
• Nausea
• Blurred vision
• Dyspepsia
• Fatigue

• Headache
• Back pain
• Dyspepsia
• Hot flashes
• Orthostatic hypotension
• Feeling weak

• The medicinal product must be stored away from heat.
• Store in the original package in order to protect from light and moisture.

• Keep this medicine out of the sight and reach of children.